The total number of records retrieved from this search are 116. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_886	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Glioblastoma cell line	U-87 MG	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.1 pfu/ml	85% cncer cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_889	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Glioblastoma cell line	U-87 MG	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.1 pfu/ml	90% cncer cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_892	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Glioblastoma cell line	U-87 MG	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.01 pfu/ml	75% cncer cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_895	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Glioblastoma cell line	U-87 MG	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.01 pfu/ml	80% cncer cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_1170	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (0.001 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	85% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1171	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (0.01 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	75% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1172	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (0.1 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	65% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1173	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (10 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	40% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1174	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (100 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1175	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (1000 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1176	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (0.001 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	65% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1177	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (0.01 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	55% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1178	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (0.1 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	30% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1179	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (10 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	10% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1180	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (100 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1181	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (1000 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1182	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (0.01 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	90% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1183	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (0.1 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	60% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1184	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (10 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	30% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1185	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (1000 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1186	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (0.01 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	70% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1187	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (0.1 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	30% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1188	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (10 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	20% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1189	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (1000 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1190	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (5mg/kg for 5 days)	No	ATCC	Human glioblastoma cell line	U-87 MG	NA	NA	NA	NA	NA	Athymic nude mice xenograft for U87MG cells	1.0E+7 pfu	NA	Complete reduction of tumor after 90 days in 20-40% of animals	NA	NA	NA	NA	17557108
OV_1191	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (7.5mg/kg for 5 days)	No	ATCC	Human glioblastoma cell line	U-87 MG	NA	NA	NA	NA	NA	Athymic nude mice xenograft for U87MG cells	1.0E+7 pfu	NA	Complete reduction of tumor after 90 days in 20-40% of animals	NA	NA	NA	NA	17557108
OV_3054	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human glioblastoma cell line	U-87 MG	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	30% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3055	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human glioblastoma cell line	U-87 MG	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	10% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3056	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human glioblastoma cell line	U-87 MG	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	1% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3084	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human glioblastoma cell line	U-87 MG	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	30% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3085	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human glioblastoma cell line	U-87 MG	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	15% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3086	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human glioblastoma cell line	U-87 MG	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	5% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_4284	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human glioblastoma	U-87 MG	4000 cells per well	NA	MTT assay	10 pfu	32.4 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4424	Vesicular stomatitis virus	RdB	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker	Yes	No	No	ATCC	Human brain cancer cell line	U-87 MG	1.2E+4 cells per well	NA	MTT assay	21:1 particle to pfu	52% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4432	Vesicular stomatitis virus	RdB-1L-VSVG	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker	Yes	No	No	ATCC	Human brain cancer cell line	U-87 MG	1.2E+4 cells per well	NA	MTT assay	24:1 particle to pfu	30% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_5341	Newcastle disease virus	LaSota	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human glioblastoma multiforme	U-87 MG	5.0E+4 cells per well	NA	MTT assay	0.001 MOI	19% cells remain viable after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	Induced production of IFN-alpha, IFN-beta, IL-6and IFN-gamma	NA	28293547
OV_5460	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	60% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5461	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	30% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5462	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	5% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5463	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 4	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5464	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 5	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5465	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 6	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5466	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	100% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5467	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	75% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5468	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	60% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5469	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	30% cell survival after day 4	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5470	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	10% cell survival after day 5	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5471	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	100% cell death after day 6	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5472	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	35% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5473	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	20% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5474	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 3	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5475	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 4	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5476	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 5	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5477	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 6	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5478	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	90% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5479	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	58% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5480	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	50% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5481	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	20% cell survival after day 4	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5482	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	5% cell survival after day 5	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5483	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	100% cell death after day 6	No	No	NA	No response	NA	NA	NA	NA	US5585096
OV_5484	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	NA	NA	NA	Balb/c mice xenograft for U-87MG	5.0E+7 pfu	NA	Reduction in tumor growth below 2%	Intraneoplastic	NA	NA	NA	US5585096
OV_5485	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5 and ICP6 gene	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	NA	NA	NA	Balb/c mice xenograft for U-87MG	5.0E+7 pfu	NA	Reduction in tumor growth below 5%	Intraneoplastic	NA	NA	NA	US5585096
OV_5486	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	60% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5487	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	30% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5488	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	5% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5489	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 4	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5490	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 5	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5491	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 6	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5492	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	100% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5493	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	75% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5494	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	60% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5495	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	30% cell survival after day 4	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5496	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	10% cell survival after day 5	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5497	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	100% cell death after day 6	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5498	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	35% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5499	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	20% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5500	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 3	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5501	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 4	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5502	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 5	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5503	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 6	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5504	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	90% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5505	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	58% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5506	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	50% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5507	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	20% cell survival after day 4	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5508	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	5% cell survival after day 5	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5509	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	100% cell death after day 6	No	No	NA	No response	NA	NA	NA	NA	US5728379
OV_5510	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	NA	NA	NA	Balb/c mice xenograft for U-87MG	5.0E+7 pfu	NA	Reduction in tumor growth below 2%	Intraneoplastic	NA	NA	NA	US5728379
OV_5511	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP4 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	NA	NA	NA	Balb/c mice xenograft for U-87MG	5.0E+7 pfu	NA	Reduction in tumor growth below 5%	Intraneoplastic	NA	NA	NA	US5728379
OV_5512	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	60% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5513	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	30% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5514	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	5% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5515	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 4	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5516	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 5	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5517	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 6	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5518	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	100% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5519	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	75% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5520	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	60% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5521	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	30% cell survival after day 4	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5522	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	10% cell survival after day 5	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5523	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	100% cell death after day 6	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5524	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	35% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5525	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	20% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5526	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 3	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5527	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 4	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5528	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 5	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5529	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	1 MOI	100% cell death after day 6	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5530	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	90% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5531	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	58% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5532	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	50% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5533	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	20% cell survival after day 4	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5534	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	5% cell survival after day 5	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5535	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	Trypan blue cell exclusion assay	0.01 MOI	100% cell death after day 6	No	No	NA	No response	NA	NA	NA	NA	US6139834
OV_5536	Herpes simplex virus	G207-1	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	NA	NA	NA	Balb/c mice xenograft for U-87MG	5.0E+7 pfu	NA	Reduction in tumor growth below 2%	Intraneoplastic	NA	NA	NA	US6139834
OV_5537	Herpes simplex virus	G207-2	DNA	Herpesviridae	Deletion mutant for gamma 34.5, ICP6 gene and ibonucleotide reductase	Yes	No	No	ATCC	Human glioma cell line	U-87 MG	NA	NA	NA	NA	NA	Balb/c mice xenograft for U-87MG	5.0E+7 pfu	NA	Reduction in tumor growth below 5%	Intraneoplastic	NA	NA	NA	US6139834
OV_5613	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human glioblastoma cell line	U-87 MG	80% confluency	NA	MTT assay	25 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5833	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human glioblastoma cell line	U-87 MG	80% confluency	NA	NA	25 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578